Occupational exposures and risk of adenocarcinoma of the lung in Uruguay

Cancer Causes Control. 2005 Sep;16(7):851-6. doi: 10.1007/s10552-005-2819-4.


Objectives: To investigate occupational risks of lung adenocarcinoma in Uruguay and to confirm a previously reported increased risk among butchers.

Methods: We conducted a case-control study among men in four major hospitals in Montevideo, based on interviews to 338 cases of lung adenocarcinoma and 1014 hospital-based controls. We calculated odds ratios (ORs) of lung adenocarcinoma for employment in 22 jobs, after adjustment for tobacco smoking and other potential confounders.

Results: The OR was increased for employment as farmer, tractor driver, painter and medical worker, but no trend was suggested for duration of employment. Long-term employment as mason, glass worker or textile worker resulted in an increased OR. The OR for employment as butcher was 1.2 (95% confidence interval 0.7-2.1). The OR increased with increasing duration of self-reported exposure to formaldehyde.

Conclusions: Occupational exposures seem to play a limited role in causing lung adenocarcinoma among men in Uruguay. Employment as butcher was not confirmed as an important risk factor.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenocarcinoma / epidemiology*
  • Adenocarcinoma / etiology*
  • Adult
  • Aged
  • Aged, 80 and over
  • Asbestos / adverse effects
  • Carcinogens
  • Case-Control Studies
  • Dust
  • Humans
  • Lung Neoplasms / epidemiology*
  • Lung Neoplasms / etiology*
  • Male
  • Meat / adverse effects
  • Middle Aged
  • Occupational Exposure / adverse effects*
  • Occupational Exposure / classification
  • Odds Ratio
  • Risk Factors
  • Silicon Dioxide / adverse effects
  • Smoking / adverse effects
  • Textiles / adverse effects
  • Uruguay / epidemiology


  • Carcinogens
  • Dust
  • Asbestos
  • Silicon Dioxide