Lambda integrase: armed for recombination

Curr Biol. 2005 Sep 6;15(17):R658-60. doi: 10.1016/j.cub.2005.08.031.


Bacteriophage lambda moves its viral genome into and out of the bacterial chromosome using site-specific recombination. Crystal structures of reaction intermediates in this recombination pathway provide exciting new snapshots of full length lambda integrase interacting with both core and regulatory DNA elements.

Publication types

  • Review

MeSH terms

  • Bacteriophage lambda / enzymology*
  • Bacteriophage lambda / genetics*
  • DNA / metabolism*
  • Integrases / metabolism*
  • Models, Biological*
  • Recombination, Genetic / genetics*
  • Virus Integration / physiology*


  • DNA
  • Integrases