[Management of pregnancies beyond forty-one week's gestation with an unfavorable cervix]

J Gynecol Obstet Biol Reprod (Paris). 2005 Sep;34(5):454-62. doi: 10.1016/s0368-2315(05)82853-4.
[Article in French]


Objective: Our purpose was to determine the optimal management of pregnancies beyond 41 week's gestation with a cervix unfavorable for induction.

Material and method: All uncomplicated pregnancies that reached 41 weeks'gestation with a Bishop score of< or =4, were randomly assigned to one of two groups

Results: The duration of labor was shorter in the group "prépidil" compared with the control group (P=0.002). Identification of an unfavorable cervix at 41 weeks was unlikely to change by 42 weeks and cervical ripening was required in 40% cases. There was no significant difference in caesarean section rates. Rates of admission into the neonatal unit and fetal outcomes were similar in the two groups.

Conclusion: Cervical ripening with prostaglandin gel at 41 week's gestation for uncomplicated singleton pregnancies is safe and should be advocated.

Publication types

  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Cervical Ripening / drug effects
  • Cervix Uteri / physiology*
  • Dinoprostone / administration & dosage
  • Female
  • Fetal Macrosomia / epidemiology
  • Humans
  • Infant Mortality
  • Infant, Newborn
  • Length of Stay
  • Pregnancy
  • Pregnancy Outcome
  • Pregnancy, Prolonged*


  • Dinoprostone