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Clinical Trial
, 49 (3), 315-9

Finger-length Ratios Show Evidence of Prenatal Hormone-Transfer Between Opposite-Sex Twins

Affiliations
Clinical Trial

Finger-length Ratios Show Evidence of Prenatal Hormone-Transfer Between Opposite-Sex Twins

Sari M van Anders et al. Horm Behav.

Abstract

Finger-length ratio (second to fourth finger; 2D:4D) has been associated with various measures thought to be related to prenatal androgens. In addition, hormone-transfer theory posits that hormones can transfer between twins. We examined 2D:4D in same-sex (SS) and opposite-sex (OS) dizygotic twins to test both propositions. Results show that 2D:4D is masculinized in OS females compared to SS females. This provides strong evidence that 2D:4D is laid down prenatally, and that hormones (likely androgens) can transfer from male to female fetuses. Implications for developmental timeframes for both hormone-transfer and 2D:4D are discussed.

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