[Protective effects of astragali injection on tubular in patients with primary nephrotic syndrome]

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2004 Apr;29(2):152-3.
[Article in Chinese]

Abstract

Objective: To determine the effects of astragali injection on tubular and its possible mechanisms.

Methods: Sixty patients with primary nephritic syndrome (PNS) were randomly divided into astragali group (n = 30) and control group (n = 30). The surm albumin (sALB) and urinary excretion of retinol-binding protein (RBP), N-Acety-P-beta-Glucosaminidase (NAG), beta2- Microglobulin (beta2MG) were measured before and after the treatment.

Results: After the one month treatment, sALB was significantly higher, and ubeta2MG, uNAG, uRBP, and 24 huP were significantly lower in astragali group (P <0.01, P < 0.05).

Conclusion: Astragali injection on tubular plays a protective role in PNS.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Acetylglucosaminidase / urine
  • Adolescent
  • Adult
  • Astragalus propinquus*
  • Child
  • Drugs, Chinese Herbal / administration & dosage*
  • Female
  • Humans
  • Injections
  • Kidney Function Tests
  • Kidney Tubules / physiopathology*
  • Male
  • Middle Aged
  • Nephrotic Syndrome / drug therapy*
  • Nephrotic Syndrome / physiopathology
  • Protective Agents / administration & dosage
  • Retinol-Binding Proteins / urine
  • Serum Albumin / analysis
  • beta 2-Microglobulin / urine

Substances

  • Drugs, Chinese Herbal
  • Protective Agents
  • Retinol-Binding Proteins
  • Serum Albumin
  • beta 2-Microglobulin
  • Acetylglucosaminidase