Staphylococcus aureus as a risk factor for bloodstream infection in children with postoperative mediastinitis

Pediatr Infect Dis J. 2005 Sep;24(9):834-7. doi: 10.1097/01.inf.0000176615.77854.7a.

Abstract

Bloodstream infection (BSI) complicates postoperative mediastinitis in >50% of cases. In this retrospective cohort study from 1995-2003, postoperative mediastinitis caused by Staphylococcus aureus was an independent risk factor for the development of BSI (adjusted odds ratio, 6.4; 95% confidence interval, 1.4-29.3). Postoperative mediastinitis caused by S. aureus has a higher intrinsic risk of being complicated by BSI than mediastinitis caused by other pathogens.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Age Distribution
  • Anti-Bacterial Agents / therapeutic use
  • Bacteremia / diagnosis
  • Bacteremia / drug therapy
  • Bacteremia / epidemiology*
  • Child
  • Child, Preschool
  • Cohort Studies
  • Female
  • Humans
  • Incidence
  • Infant
  • Infant, Newborn
  • Male
  • Mediastinitis / drug therapy
  • Mediastinitis / epidemiology*
  • Mediastinitis / microbiology*
  • Odds Ratio
  • Probability
  • Reference Values
  • Retrospective Studies
  • Risk Assessment
  • Sex Distribution
  • Staphylococcal Infections / diagnosis*
  • Staphylococcal Infections / drug therapy
  • Staphylococcal Infections / epidemiology
  • Staphylococcus aureus / isolation & purification*
  • Surgical Wound Infection / drug therapy
  • Surgical Wound Infection / epidemiology*
  • Surgical Wound Infection / microbiology
  • Survival Rate
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents