Abstract
Chlamydomonas flagella contain a molecular chaperone now identified as HSP70A, a major cytoplasmic isoform. HSP70A synthesis is upregulated by deflagellation, and its distribution in the flagellum overlaps with the IFT kinesin-II motor FLA10. HSP70A may chaperone flagellar proteins during transport, participating in the assembly and maintenance of the flagellum.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Animals
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Chlamydomonas reinhardtii / physiology*
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Flagella / metabolism*
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HSP70 Heat-Shock Proteins / genetics
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HSP70 Heat-Shock Proteins / metabolism*
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Microtubule-Associated Proteins / metabolism
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Molecular Chaperones*
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Protein Transport
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Protozoan Proteins / metabolism
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RNA, Messenger / genetics
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RNA, Messenger / metabolism
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RNA, Protozoan / genetics
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RNA, Protozoan / metabolism
Substances
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HSP70 Heat-Shock Proteins
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KHP1 protein, Chlamydomonas
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Microtubule-Associated Proteins
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Molecular Chaperones
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Protozoan Proteins
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RNA, Messenger
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RNA, Protozoan