Change in bacterial aetiology of peritoneal dialysis-related peritonitis over 10 years: experience from a centre in South-East Asia

Clin Microbiol Infect. 2005 Oct;11(10):837-9. doi: 10.1111/j.1469-0691.2005.01222.x.


This study reviewed 1787 episodes of peritoneal dialysis (PD)-related peritonitis in 544 patients between 1994 and 2003. The overall rate of peritonitis was 0.68 episodes/year of PD, but decreased from 1.10 to 0.46 episodes/year between 1994 and 2003. The incidence of peritonitis caused by coagulase-negative staphylococci declined between 1994 and 1998 from 0.21 to 0.06 episodes/year of PD, coinciding with a reduction in the use of spike PD sets. There was a 60.1% response rate to antibiotics throughout the period, but the percentage of cases that required modification of the initial empirical antibiotic regimen rose from 13.6% to 58.7%, indicating that treatment should be individualised.

Publication types

  • Review

MeSH terms

  • Asia, Southeastern
  • Humans
  • Peritoneal Dialysis / adverse effects*
  • Peritonitis / microbiology*
  • Staphylococcal Infections / epidemiology
  • Staphylococcal Infections / etiology*
  • Staphylococcus / enzymology
  • Staphylococcus / isolation & purification