Some current issues in breast cancer screening

J Med Screen. 2005;12(3):128-33. doi: 10.1258/0969141054855319.


Randomized trials of mammography have demonstrated the efficacy of mammographic screening for breast cancer in terms of preventing deaths, but various issues of particular interest remain, including: quantification of overdiagnosis; evaluation of service screening outside the research setting; absolute benefit in terms of number needed to screen per life saved; which types of tumours benefit most from early detection; use of screening data to investigate tumour biology and natural history. This paper describes examples of approaches to the above issues, along with some important results.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Breast Neoplasms / diagnosis*
  • Case-Control Studies
  • Female
  • Humans
  • Mammography / methods*
  • Mass Screening / methods*
  • Mass Screening / trends
  • Middle Aged
  • Models, Theoretical
  • Neoplasm Invasiveness
  • Research Design
  • Risk
  • Time Factors