Fatal case of Naegleria fowleri meningo-encephalitis in an infant: case report

Ann Trop Paediatr. 2005 Sep;25(3):223-6. doi: 10.1179/146532805X58166.


Primary amoebic meningo-encephalitis (PAM) is extremely rare and is caused by Naegleria fowleri. It is ?commonly seen in older children who swim in water contaminated with Naegleria species. It is very rare to contract the illness by any other means. We report a case of PAM in an infant aged 6 months. To the best of our knowledge, only one other case of PAM in an infant has been reported from India. A high index of suspicion is required in infants who manifest similarly to pyogenic meningitis but whose CSF shows no bacterial organisms so that a wet mount of a CSF sample can be done for early detection of Naegleria fowleri infection and appropriate intervention.

Publication types

  • Case Reports

MeSH terms

  • Amebiasis / drug therapy
  • Amebiasis / parasitology*
  • Animals
  • Central Nervous System Protozoal Infections / drug therapy
  • Central Nervous System Protozoal Infections / parasitology*
  • Fatal Outcome
  • Humans
  • Infant
  • Male
  • Meningoencephalitis / drug therapy
  • Meningoencephalitis / parasitology*
  • Naegleria fowleri*