Disseminated Ochroconis gallopavum infection in a chronic lymphocytic leukemia: a case report and review of the literature on hematological malignancies

Intern Med. 2005 Aug;44(8):879-82. doi: 10.2169/internalmedicine.44.879.


Disseminated fungal infection is an important cause of morbidity and mortality among patients with hematological malignancies. Ochroconis gallopavum is a dematiaceous and thermotolerant fungus that causes opportunistic infections in immunocompromised hosts. About only 30 cases of this organism infection have been reported worldwide. We report a disseminated Ochroconis gallopavum infection in a B-cell chronic lymphocytic leukemia patient. In spite of intensive anti-fungal treatment, no improvement in the clinical condition was observed and the patient died 4 months after diagnosis of the infection. Ochroconis gallopavum infection is a potentially fatal disease in hematological malignancies.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Aged
  • Antifungal Agents / therapeutic use
  • Ascomycota* / isolation & purification
  • Fatal Outcome
  • Female
  • Hematologic Neoplasms / complications
  • Humans
  • Immunocompromised Host
  • Leukemia, Lymphocytic, Chronic, B-Cell / complications*
  • Leukemia, Lymphocytic, Chronic, B-Cell / immunology
  • Mycoses / complications*
  • Mycoses / drug therapy
  • Mycoses / microbiology
  • Opportunistic Infections / complications*
  • Opportunistic Infections / drug therapy
  • Opportunistic Infections / microbiology


  • Antifungal Agents