Evolutionary and diagnostic implications of intragenomic heterogeneity in the 16S rRNA gene in Aeromonas strains

J Bacteriol. 2005 Sep;187(18):6561-4. doi: 10.1128/JB.187.18.6561-6564.2005.


Sequencing 16S rRNA genes (SSU) cloned from Aeromonas strains revealed that strains contained up to six copies differing by < or = 1.5%. The SSU copies from Aeromonas veronii LMG13695 clustered with sequences from four Aeromonas species. These results demonstrate intragenomic heterogeneity of SSU and suggest caution when using SSU to identify aeromonads.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Aeromonas / classification*
  • Aeromonas / genetics
  • DNA, Intergenic / analysis*
  • Evolution, Molecular*
  • Genetic Heterogeneity*
  • Genome, Bacterial*
  • Phylogeny
  • RNA, Ribosomal, 16S / analysis*
  • RNA, Ribosomal, 16S / genetics
  • Sequence Analysis, DNA


  • DNA, Intergenic
  • RNA, Ribosomal, 16S