Purpose: To report suspected donor-to-host transmission of Cryptococcus albidus after penetrating keratoplasty.
Methods: Review of the literature and a case report of a 69-year-old woman who underwent penetrating keratoplasty for Fuchs corneal dystrophy and developed persistent corneal infiltrates 7 months postoperatively are presented.
Results: Cryptococcus albidus was cultured from the original donor tissue at the time of the repeat keratoplasty.
Conclusion: This case demonstrates an unusual case of cryptococcal keratitis after keratoplasty suspected to be a donor-to-host transmission.