Clinical applications of neuroimaging with susceptibility-weighted imaging

J Magn Reson Imaging. 2005 Oct;22(4):439-50. doi: 10.1002/jmri.20404.


Susceptibility-weighted imaging (SWI) consists of using both magnitude and phase images from a high-resolution, three-dimensional, fully velocity compensated gradient-echo sequence. Postprocessing is applied to the magnitude image by means of a phase mask to increase the conspicuity of the veins and other sources of susceptibility effects. This article gives a background of the SWI technique and describes its role in clinical neuroimaging. SWI is currently being tested in a number of centers worldwide as an emerging technique to improve the diagnosis of neurological trauma, brain neoplasms, and neurovascular diseases because of its ability to reveal vascular abnormalities and microbleeds.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Brain Injuries / diagnosis
  • Brain Neoplasms / diagnosis
  • Brain*
  • Cerebrovascular Disorders / diagnosis
  • Contrast Media
  • Humans
  • Intracranial Arteriovenous Malformations / diagnosis
  • Magnetic Resonance Imaging / methods*
  • Models, Theoretical
  • Neurodegenerative Diseases / diagnosis


  • Contrast Media