Presurgical curettage appropriately reduces the number of Mohs stages by better delineating the subclinical extensions of tumor margins

Dermatol Surg. 2005 Sep;31(9 Pt 1):1094-9; discussion 1100. doi: 10.1097/00042728-200509000-00002.

Abstract

Background: Whether presurgical curettage (PC), light curettage performed before Mohs surgery to delineate tumor margin, is appropriate or causes unnecessary removal of normal tissue has not been well established.

Objective: We aim to determine histologically whether PC appropriately increases the size of the stage I specimen or causes unnecessary removal of healthy tissue.

Methods: Before a surgical margin guided by PC was taken, a hypothetical margin determined by visual and tactile assessment alone (no curettage [NC]) was marked outside the clinically defined tumor. Histologic analysis at the NC and the PC margins revealed whether the increase in the stage I specimen as a result of PC was appropriate.

Results: PC appropriately increased the stage I specimen in 21 cases and unnecessarily removed normal tissue in only 1 case. The estimation of tumor margins with PC was 15 times more accurate than with NC (p value = .0012).

Conclusion: For basal cell and squamous cell carcinomas at least 4 mm in diameter, light curettage performed prior to Mohs surgery could better delineate subclinical extensions of the tumor margin and appropriately increase the size of the stage I specimen.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Carcinoma, Basal Cell / pathology*
  • Carcinoma, Basal Cell / surgery
  • Carcinoma, Squamous Cell / pathology*
  • Carcinoma, Squamous Cell / surgery
  • Curettage / methods*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Mohs Surgery
  • Neoplasm Staging
  • Preoperative Care
  • Prospective Studies
  • Skin Neoplasms / pathology*
  • Skin Neoplasms / surgery
  • Treatment Outcome