Staged sentinel lymph node biopsy before mastectomy facilitates surgical planning for breast cancer patients

Am J Surg. 2005 Oct;190(4):595-7. doi: 10.1016/j.amjsurg.2005.06.020.

Abstract

Background: In patients with breast cancer who choose mastectomy with immediate reconstruction, the sentinel lymph node (SLN) status on permanent histology may complicate treatment if a metastasis is found. The purpose of this study was to determine how performing an SLN biopsy (SLNB) before the definitive operation would influence subsequent surgical procedures.

Methods: Our SLN database was searched for patients who underwent staged SLNB with subsequent mastectomy between 2001 and 2004.

Results: Twenty-five patients with 27 breast cancers underwent SLNB before mastectomy. Of them, 9 of 27 (33%) were node positive. All 9 patients underwent modified radical mastectomy. Three node-positive patients did not undergo immediate reconstruction. Of the remaining 6 node-positive patients, 5 underwent reconstruction with autologous tissue rather than a tissue expander. In contrast, 6 of 16 (37%) node-negative patients underwent reconstruction with a tissue expander.

Conclusions: Staged SLNB assists in selecting the appropriate operation in patients who are considering immediate reconstruction.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Axilla
  • Breast Neoplasms / pathology*
  • Breast Neoplasms / therapy
  • Carcinoma, Ductal, Breast / pathology*
  • Carcinoma, Ductal, Breast / therapy
  • Carcinoma, Intraductal, Noninfiltrating / pathology*
  • Carcinoma, Intraductal, Noninfiltrating / therapy
  • Carcinoma, Lobular / pathology*
  • Carcinoma, Lobular / therapy
  • Female
  • Humans
  • Lymph Node Excision
  • Lymphatic Metastasis
  • Mammaplasty
  • Mastectomy
  • Middle Aged
  • Neoplasm Staging
  • Radiotherapy, Adjuvant
  • Sentinel Lymph Node Biopsy / methods*