GADD45 deregulation in cancer: frequently methylated tumor suppressors and potential therapeutic targets

Clin Cancer Res. 2005 Sep 15;11(18):6409-13. doi: 10.1158/1078-0432.CCR-05-1475.
No abstract available

Publication types

  • Comment

MeSH terms

  • Amino Acid Sequence
  • Antimetabolites, Antineoplastic / pharmacology
  • Azacitidine / analogs & derivatives
  • Azacitidine / pharmacology
  • Cell Cycle Proteins / genetics*
  • Cell Line
  • Cell Line, Tumor
  • CpG Islands / genetics
  • DNA Methylation / drug effects
  • DNA Modification Methylases / antagonists & inhibitors
  • Decitabine
  • Gene Expression Regulation, Neoplastic / drug effects
  • Humans
  • Models, Biological
  • Molecular Sequence Data
  • Neoplasms / drug therapy
  • Neoplasms / genetics*
  • Neoplasms / pathology
  • Nuclear Proteins / genetics*
  • Prognosis
  • Promoter Regions, Genetic / genetics
  • Sequence Homology, Amino Acid
  • Tumor Suppressor Proteins / genetics

Substances

  • Antimetabolites, Antineoplastic
  • Cell Cycle Proteins
  • GADD45A protein, human
  • Nuclear Proteins
  • Tumor Suppressor Proteins
  • Decitabine
  • DNA Modification Methylases
  • Azacitidine