Opinion: The Maturing Role of COPI Vesicles in intra-Golgi Transport

Nat Rev Mol Cell Biol. 2005 Oct;6(10):812-7. doi: 10.1038/nrm1735.


COPI vesicles that surround the Golgi stack were first implicated in the anterograde movement of cargo, and then in the retrograde movement of Golgi enzymes. Recently, their role has been challenged again, and we discuss new data that both confirm and modify our view of these carriers.

Publication types

  • Review

MeSH terms

  • Animals
  • Biological Transport, Active / physiology
  • COP-Coated Vesicles / metabolism*
  • COP-Coated Vesicles / ultrastructure
  • Cell Compartmentation / physiology
  • Cell Line, Tumor
  • Dendritic Cells / metabolism
  • Dendritic Cells / ultrastructure
  • Golgi Apparatus / enzymology*
  • Golgi Apparatus / ultrastructure
  • Humans