Reference values for renal concentrating capacity in children by the desmopressin test

Pediatr Nephrol. 1992 May;6(3):254-7. doi: 10.1007/BF00878361.


Reference values are reported for maximal renal concentrating capacity in children using intranasally administered desmopressin. The report is based on 591 tests in 473 healthy children aged 0.5-13 years. The concentrating capacity increased markedly during the first years of life and reached a plateau at the age of 3 years. The mean value minus two standard deviations was 525 mosmol/kg at 1 year of age and 825 mosmol/kg at 3 years of age.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Intranasal
  • Adolescent
  • Child
  • Child, Preschool
  • Deamino Arginine Vasopressin* / administration & dosage
  • Humans
  • Infant
  • Kidney Concentrating Ability*
  • Methods
  • Reference Values
  • Statistics as Topic
  • Sweden


  • Deamino Arginine Vasopressin