Abstract
The crystal structure of a homolog of oxysterol binding protein solved by Jim Hurley and coworkers (Im et al., 2005) shows that this large family acts as cholesterol transporters, taking not only the lipid but also large numbers of water molecules into an internal pocket.
MeSH terms
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Fungal Proteins / genetics
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Fungal Proteins / metabolism
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Humans
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Membrane Proteins / chemistry
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Membrane Proteins / genetics
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Membrane Proteins / metabolism
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Models, Molecular
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Plant Proteins / genetics
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Plant Proteins / metabolism
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Receptors, Steroid / genetics
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Receptors, Steroid / metabolism
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Saccharomyces cerevisiae Proteins / chemistry
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Saccharomyces cerevisiae Proteins / genetics
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Saccharomyces cerevisiae Proteins / metabolism
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Sterols / chemistry*
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Water / chemistry*
Substances
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Fungal Proteins
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KES1 protein, S cerevisiae
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Membrane Proteins
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Plant Proteins
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Receptors, Steroid
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Saccharomyces cerevisiae Proteins
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Sterols
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Water