Screening the SPO11 and EIF5A2 genes in a population of infertile men

Fertil Steril. 2005 Sep;84(3):758-60. doi: 10.1016/j.fertnstert.2005.03.053.

Abstract

Populations of infertile and fertile men were screened for mutations in SPO11 and EIF5A2, two infertility candidate genes. Three heterozygous amino acid changes that might contribute to infertility were identified in the infertile group.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Endodeoxyribonucleases
  • Esterases / genetics*
  • Genetic Testing / methods*
  • Humans
  • Infertility, Male / genetics*
  • Male
  • Mutation
  • Peptide Initiation Factors / genetics*
  • RNA-Binding Proteins / genetics*

Substances

  • Peptide Initiation Factors
  • RNA-Binding Proteins
  • eukaryotic translation initiation factor 5A
  • Endodeoxyribonucleases
  • Esterases
  • meiotic recombination protein SPO11