Nosocomial bacteremia due to Enterococcus faecalis without endocarditis

Clin Infect Dis. 1992 Jul;15(1):49-57. doi: 10.1093/clinids/15.1.49.


During a 2-year observation period at a 2,200-bed university hospital, bacteremia due to Enterococcus faecalis was observed in 111 patients. Fifty-five patients with nosocomial bacteremia due to E. faecalis could be evaluated. The most common entry sites were the urinary tract (25%), the intraabdominal cavity (13%), and burn and decubital wounds (11%). Bacteremia was preceded by administration of cephalosporins, imipenem, and aztreonam (n = 39); ciprofloxacin (n = 11); and other antibiotics (n = 4). Age, sex, underlying disease, portal of entry, previous antibiotic therapy, and bacteremia due to other organisms had no influence on mortality. Treatment of bacteremia with penicillins (n = 45) and glycopeptides (n = 4) resulted in a mortality rate of 37%. The addition of a high-dose aminoglycoside to a penicillin did not result in a better survival rate.

Publication types

  • Review

MeSH terms

  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Austria
  • Bacteremia / drug therapy
  • Bacteremia / microbiology*
  • Bacteriological Techniques
  • Cross Infection / drug therapy
  • Cross Infection / microbiology*
  • Endocarditis, Bacterial
  • Enterococcus faecalis*
  • Female
  • Gram-Positive Bacterial Infections* / drug therapy
  • Hospital Bed Capacity, 500 and over
  • Hospitals, University
  • Humans
  • Male
  • Middle Aged
  • Survival Analysis


  • Anti-Bacterial Agents