A preliminary survey of Atopobium vaginae in women attending the Dunedin gynaecology out-patients clinic: is the contribution of the hard-to-culture microbiota overlooked in gynaecological disorders?

Aust N Z J Obstet Gynaecol. 2005 Oct;45(5):450-2. doi: 10.1111/j.1479-828X.2005.00456.x.


Preliminary studies have indicated that the recently described bacterium Atopobium vaginae may have an association with bacterial vaginosis (BV). Fifty-five women attending the gynaecology out-patient's clinic were tested for the presence of this micro-organism, Gardnerella vaginalis, Mobiluncus and Bacteroides species by polymerase chain reaction (PCR)-based assays. The frequency of detection was 40%. PCR detection of Gardnerella vaginalis with A. vaginae, occurred in 50% of A. vaginae-positive cases. Due to the high detection rate of A. vaginae we believe that it is important to determine whether this and other hard-to-culture microorganisms have a role in gynaecological disorders.

Publication types

  • Comparative Study

MeSH terms

  • Actinobacteria / classification*
  • Actinobacteria / isolation & purification*
  • Adolescent
  • Adult
  • Age Distribution
  • Aged
  • Ambulatory Care Facilities
  • Cohort Studies
  • DNA, Bacterial / analysis
  • Female
  • Health Surveys
  • Humans
  • Incidence
  • Middle Aged
  • New Zealand / epidemiology
  • Polymerase Chain Reaction
  • Prognosis
  • Severity of Illness Index
  • Vaginosis, Bacterial / diagnosis*
  • Vaginosis, Bacterial / epidemiology*


  • DNA, Bacterial