Accidental provocation of phaeochromocytoma: the forgotten hazard of metoclopramide?

Singapore Med J. 2005 Oct;46(10):557-60.

Abstract

The perilous potential of metoclopramide when used inadvertently in patients harbouring phaeochromocytomas goes largely under-recognised. Despite the rarity of phaeochromocytoma, clinicians should exercise caution in the use of metoclopramide among hypertensives and those with labile blood pressures, given the potentially life-threatening crisis it can readily evoke in those with this tumour. We report a series of three patients with phaeochromocytoma who developed acute crises from metoclopramide.

Publication types

  • Case Reports

MeSH terms

  • Adrenal Gland Neoplasms / chemically induced*
  • Adult
  • Antiemetics
  • Contraindications
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Metoclopramide / adverse effects*
  • Middle Aged
  • Pheochromocytoma / chemically induced*

Substances

  • Antiemetics
  • Metoclopramide