Toenail selenium concentrations and bladder cancer risk in women and men

Br J Cancer. 2005 Oct 3;93(7):804-6. doi: 10.1038/sj.bjc.6602788.


Prediagnostic selenium concentrations measured in archived toenails were inversely associated with bladder cancer risk in women (P for trend = 0.02), but not in men, in a nested case-control study of 338 cases and 341 matched controls. These findings may be due to chance and more studies are needed to determine whether associations between selenium and bladder cancer risk differ by sex.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Case-Control Studies
  • Cohort Studies
  • Female
  • Humans
  • Male
  • Nails / chemistry*
  • Risk Factors
  • Selenium / analysis*
  • Urinary Bladder Neoplasms / etiology*


  • Selenium