Sensitization to airborne environmental allergens: unresolved issues

Nat Immunol. 2005 Oct;6(10):957-60. doi: 10.1038/ni1005-957.

Abstract

Despite considerable advances in identifying the environmental agents that trigger allergy and the immunological mechanisms involved, progress in developing effective treatments remains frustratingly slow. Is it time to rethink some of the paradigms guiding this research?

Publication types

  • Review

MeSH terms

  • Air Pollutants / adverse effects*
  • Air Pollutants / immunology
  • Allergens / adverse effects*
  • Allergens / immunology
  • Animals
  • Antigens / adverse effects*
  • Antigens / immunology
  • Cytokines / antagonists & inhibitors
  • Humans
  • Hypersensitivity / etiology*
  • Hypersensitivity / therapy*
  • Immunization*
  • T-Lymphocytes, Helper-Inducer / immunology*

Substances

  • Air Pollutants
  • Allergens
  • Antigens
  • Cytokines