NMR in vitro effects on proliferation, apoptosis, and viability of human chondrocytes and osteoblasts

Methods Find Exp Clin Pharmacol. 2005 Jul-Aug;27(6):391-4. doi: 10.1358/mf.2005.27.6.896831.


This study presents findings on the proliferation rate, cellular apoptosis, and viability of human chondrocyte and osteoblast cultures before and after treatment with NMR pulse sequences. A commercially available nuclear magnetic resonance machine (MBST(R)-Nuclear Magnetic Resonance Therapy) was used for treatment. The study was carried out for 19 days, including 9 days of NMR exposure in a controlled, double-blind, randomized manner, using commercially available human cell lines. The study revealed that NMR treatment did not induce apoptosis or inhibit cell viability, but revealed a tendency of an elevated cell proliferation rate as observed by cell count.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Apoptosis
  • Cell Line
  • Cell Proliferation*
  • Cell Survival
  • Chondrocytes
  • Double-Blind Method
  • Humans
  • Magnetic Resonance Spectroscopy*
  • Osteoblasts