Live chemical reports from the cell surface

Chem Biol. 2005 Sep;12(9):954-6; discussion 999-1006. doi: 10.1016/j.chembiol.2005.09.001.


Understanding the dynamic roles that proteins play in cell biology requires tools to selectively label these biomolecules in living systems. Yin and colleagues [1] showcase the power of a novel chemical labeling technology for tracking receptor-ligand interactions in native cellular environments.

MeSH terms

  • Cell Membrane / chemistry
  • Cell Membrane / metabolism*
  • Ligands
  • Protein Binding
  • Receptors, Transferrin / metabolism


  • Ligands
  • Receptors, Transferrin