There is increasing evidence that human cognitive functions can be addressed from a robust neuroscience perspective. In particular, the distributed coherent electrical properties of central neuronal ensembles are considered to be a promising avenue of inquiry concerning global brain functions. The intrinsic oscillatory properties of neurons (Llinás, R. (1988) The intrinsic electrophysiological properties of mammalian neurons: Insights into central nervous system function. Science, 242: 1654-1664), supported by a large variety of voltage-gated ionic conductances are recognized to be the central elements in the generation of the temporal binding required for cognition. Research in neuroscience further indicates that oscillatory activity in the gamma band (25-50 Hz) can be correlated with both sensory acquisition and pre-motor planning, which are non-continuous functions in the time domain. From this perspective, gamma-band activity is viewed as serving a broad temporal binding function, where single-cell oscillators and the conduction time of the intervening pathways support large multicellular thalamo-cortical resonance that is closely linked with cognition and subjective experience. Our working hypothesis is that although dedicated units achieve sensory processing, the cognitive binding process is a common mechanism across modalities. Moreover, it is proposed that such time-dependent binding when altered, will result in modifications of the sensory motor integration that will affect and impair cognition and conscious perception.