Abstract
Newer, more selective, antidepressant agents are increasingly being used as first-line treatment. However, clinical experience in patients after a deliberate overdose is limited. We present a case of venlafaxine intoxication complicated by a late rise in creatine kinase, seizures and serotonin syndrome. Rhabdomyolysis prolonged the hospital stay in our patient but had no other serious consequences. Physicians should be aware of this late phenomenon in patients with venlafaxine poisoning.
MeSH terms
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Adult
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Antidepressive Agents, Second-Generation / administration & dosage
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Antidepressive Agents, Second-Generation / adverse effects*
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Creatine Kinase / blood
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Cyclohexanols / administration & dosage
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Cyclohexanols / adverse effects*
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Delayed-Action Preparations
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Drug Overdose
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Female
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Humans
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Rhabdomyolysis / chemically induced*
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Selective Serotonin Reuptake Inhibitors / administration & dosage
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Selective Serotonin Reuptake Inhibitors / adverse effects*
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Serotonin Syndrome / chemically induced*
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Venlafaxine Hydrochloride
Substances
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Antidepressive Agents, Second-Generation
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Cyclohexanols
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Delayed-Action Preparations
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Serotonin Uptake Inhibitors
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Venlafaxine Hydrochloride
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Creatine Kinase