Linezolid treatment of ventriculoperitoneal shunt infection without implant removal

Eur J Clin Microbiol Infect Dis. 2005 Sep;24(9):603-6. doi: 10.1007/s10096-005-0015-9.


Ventriculoperitoneal shunt infection is a serious clinical problem for which implant removal is considered the treatment of choice. However, surgery is sometimes associated with considerable risks that may outweigh the benefits. Presented here is a case of ventriculoperitoneal shunt infection treated successfully with linezolid without implant removal. This case shows linezolid could be a therapeutic alternative when surgery is contraindicated.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Acetamides / therapeutic use*
  • Anti-Bacterial Agents / therapeutic use*
  • Device Removal
  • Humans
  • Linezolid
  • Male
  • Methicillin Resistance
  • Middle Aged
  • Oxazolidinones / therapeutic use*
  • Staphylococcal Infections / drug therapy*
  • Staphylococcal Infections / etiology*
  • Staphylococcus epidermidis* / drug effects
  • Staphylococcus epidermidis* / isolation & purification
  • Ventriculoperitoneal Shunt / adverse effects*


  • Acetamides
  • Anti-Bacterial Agents
  • Oxazolidinones
  • Linezolid