V-10153 (Vernalis)

Curr Opin Investig Drugs. 2005 Sep;6(9):951-5.

Abstract

Vernalis is developing V-10153, a recombinant plasminogen activator stimulator, for the potential treatment of thrombotic disorders and cardiovascular disease. By March 2004, a phase II trial in acute myocardial infarction had been completed, and by July 2005, Vernalis intended to initiate a phase II trial in stroke later that same year.

MeSH terms

  • Animals
  • Fibrinolytic Agents / therapeutic use*
  • Humans
  • Myocardial Infarction / drug therapy
  • Plasminogen / chemical synthesis
  • Plasminogen / metabolism
  • Plasminogen / pharmacology
  • Plasminogen / therapeutic use*
  • Structure-Activity Relationship

Substances

  • BB-10153
  • Fibrinolytic Agents
  • Plasminogen