Cutaneous Bipolaris infection in a neutropenic patient with acute lymphoblastic leukemia

J Cutan Med Surg. Nov-Dec 2004;8(6):446-9. doi: 10.1007/pl00021729.


Bipolaris spicifera is a darkly pigmented (dematiaceous) fungus that uncommonly causes infections in humans. There are few cases of reported cutaneous Bipolaris infection in the literature. We report a case of a five-year-old boy with B-precursor-cell acute lymphoblastic leukemia who developed a cutaneous fungal infection on his left cheek Histopathological and microbiological findings identified the fungus as Bipolaris spicifera. Surgical excision and systemic antifungal therapy are the mainstay of treatment.

Publication types

  • Case Reports

MeSH terms

  • Amphotericin B / therapeutic use
  • Antifungal Agents / therapeutic use
  • Ascomycota / isolation & purification*
  • Cheek
  • Child, Preschool
  • Dermatomycoses / drug therapy
  • Dermatomycoses / microbiology*
  • Humans
  • Male
  • Neutropenia / etiology*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications*


  • Antifungal Agents
  • Amphotericin B