Theoretical Aspects of Virus Capsid Assembly

J Mol Recognit. Nov-Dec 2005;18(6):479-90. doi: 10.1002/jmr.754.

Abstract

A virus capsid is constructed from many copies of the same protein(s). Molecular recognition is central to capsid assembly. The capsid protein must polymerize in order to create a three-dimensional protein polymer. More than structure is required to understand this self-assembly reaction: one must understand how the pieces come together in solution.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Capsid / metabolism*
  • Capsid / ultrastructure
  • Mathematics
  • Models, Biological*
  • Thermodynamics