Prolonged postictal stupor: nonconvulsive status epilepticus, medication effect, or postictal state?

Epilepsy Behav. 2005 Nov;7(3):548-51. doi: 10.1016/j.yebeh.2005.06.018. Epub 2005 Sep 27.

Abstract

We describe a patient who entered a stuporous state after receiving benzodiazepine treatment for generalized tonic-clonic status epilepticus. A diagnosis of generalized NCSE with tonic seizures was made on the basis of the clinical picture and response to barbiturate anaesthetic, although the EEG pattern was not typical of the changes previously described in tonic seizures-tonic status epilepticus. This report discusses the differential diagnosis of postictal stupor, nonconvulsive status epilepticus with tonic seizures and sedation caused by the emergency treatment of status epilepticus, and summarizes the literature on tonic seizures and tonic status epilepticus.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anticonvulsants / adverse effects*
  • Anticonvulsants / therapeutic use
  • Benzodiazepines / adverse effects
  • Benzodiazepines / therapeutic use
  • Coma / etiology*
  • Coma / psychology*
  • Diagnosis, Differential
  • Electroencephalography
  • Epilepsy, Complex Partial / complications
  • Epilepsy, Complex Partial / drug therapy
  • Epilepsy, Generalized / complications
  • Epilepsy, Generalized / drug therapy
  • Epilepsy, Tonic-Clonic / complications
  • Epilepsy, Tonic-Clonic / psychology
  • Female
  • Humans
  • Learning Disabilities / complications
  • Phenobarbital / therapeutic use
  • Seizures / complications*
  • Seizures / drug therapy
  • Seizures / psychology*
  • Status Epilepticus / psychology*
  • Thiopental / adverse effects
  • Thiopental / therapeutic use
  • Valproic Acid / therapeutic use

Substances

  • Anticonvulsants
  • Benzodiazepines
  • Valproic Acid
  • Thiopental
  • Phenobarbital