Percutaneous reaming of simple bone cysts in children followed by injection of demineralized bone matrix and autologous bone marrow

J Pediatr Orthop. Sep-Oct 2005;25(5):671-5. doi: 10.1097/01.bpo.0000164874.36770.42.


The authors report the successful treatment of 19 patients (mean age 10 years) with active unicameral bone cysts using a combination of percutaneous reaming and injection of a mixture of demineralized bone matrix and autologous bone marrow. Follow-up ranged from 12 to 42 months (mean 28 months). All patients were asymptomatic at the latest follow-up. Two required a second intervention to accomplish complete cyst healing. Radiographic outcome was improved in all patients according to the Neer classification at the latest follow-up. There were no significant complications related to the procedure, nor did any fracture occur after initiation of the above regimen.

MeSH terms

  • Adolescent
  • Bone Cysts / complications
  • Bone Cysts / diagnostic imaging
  • Bone Cysts / surgery*
  • Bone Demineralization Technique
  • Bone Marrow Transplantation*
  • Bone Matrix*
  • Child
  • Child, Preschool
  • Female
  • Follow-Up Studies
  • Fractures, Spontaneous / complications
  • Humans
  • Injections
  • Injections, Intralesional
  • Male
  • Radiography
  • Reoperation
  • Retrospective Studies
  • Transplantation, Autologous