Solitary fibrous tumour of the oral cavity with histological features of aggressiveness

Br J Oral Maxillofac Surg. 2006 Dec;44(6):543-5. doi: 10.1016/j.bjoms.2005.09.001. Epub 2005 Oct 3.

Abstract

We operated on a 65-year-old woman and removed a solitary fibrous tumour from her oral mucosa. Microscopically we found marked atypia, abundant necrosis, increased number of mitotic figures (>4 in 10 high-power fields) and hypercellularity. The tumour cells were strongly stained for CD34. There has been no recurrence after 18 months.

MeSH terms

  • 12E7 Antigen
  • Aged
  • Antigens, CD / analysis
  • Antigens, CD34 / analysis
  • Cell Adhesion Molecules / analysis
  • Female
  • Follow-Up Studies
  • Humans
  • Mitotic Index
  • Mouth Mucosa / pathology
  • Mouth Neoplasms / pathology*
  • Mouth Neoplasms / surgery
  • Necrosis
  • Neoplasms, Fibrous Tissue / pathology*
  • Neoplasms, Fibrous Tissue / surgery
  • Proto-Oncogene Proteins c-bcl-2 / analysis
  • Vimentin / analysis

Substances

  • 12E7 Antigen
  • Antigens, CD
  • Antigens, CD34
  • CD99 protein, human
  • Cell Adhesion Molecules
  • Proto-Oncogene Proteins c-bcl-2
  • Vimentin