Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
, 3 (7), 667-71

Anisakis Simplex-Induced Small Bowel Obstruction After Fish Ingestion: Preliminary Evidence for Response to Parenteral Corticosteroids

Case Reports

Anisakis Simplex-Induced Small Bowel Obstruction After Fish Ingestion: Preliminary Evidence for Response to Parenteral Corticosteroids

Laura Ramos et al. Clin Gastroenterol Hepatol.


Background & aims: Gastrointestinal anisakiasis, a fish-borne zoonoses, may be acquired by humans after the ingestion of raw marine fish infested with larvae of the nematode Anisakis simplex. Because of the invasive nature of the parasite, inflammatory obstruction or perforation of the gut wall may result. Although rare, Anisakis-induced intestinal obstruction is becoming a growing public health problem in Mediterranean areas, such as Spain, with a high fish-intake-based diet. Unawareness of this entity and nonspecific clinical symptoms, along with the lack of alternative therapeutic options other than conservative measures, may explain why half of these patients require abdominal laparotomy for diagnostic and therapeutic purposes.

Methods: We describe a series of 8 patients with acute intestinal anisakiasis treated in our center from July 2001 to January 2004.

Results: The first 3 patients underwent segmental ileal resection for imminent peritonitis. The remaining 5 patients were treated with intravenous 6-methylprednisolone (1 mg/kg/24 h) for 5 days with fast clinical and radiologic resolution in all 5 patients with no adverse reactions.

Conclusions: Although preliminary, our data may suggest that parenteral corticosteroids could be a reasonable, inexpensive, and safe alternative in these patients to prevent intestinal resection.

Similar articles

  • Intestinal Anisakiasis as a Rare Cause of Small Bowel Obstruction
    G Kojima et al. Am J Emerg Med 31 (9), 1422.e1-2. PMID 23786678. - Case Reports
    Anisakiasis, a parasitic infection by larvae of the nematode Anisakis found in raw or undercooked saltwater fish, mostly involves stomach but rarely small intestine. We r …
  • Anisakiasis of the Colon Presenting as Bowel Obstruction
    R Schuster et al. Am Surg 69 (4), 350-2. PMID 12716097. - Case Reports
    Anisakiasis is a disease caused by human infection by the Anisakis larvae, a marine nematode found in raw or undercooked fish. With the increased popularity of eating sus …
  • Anisakis Simplex: A Cause of Intestinal Pseudo-Obstruction
    J Domínguez Ortega et al. Rev Esp Enferm Dig 92 (3), 132-9. PMID 10799943.
    in our patients with intestinal pseudo-obstruction and a history of frequent fish eating, the clinical and laboratory findings were suggestive of parasitization by Anisak …
  • [Gastrointestinal Anisakiasis. Study of a Series of 25 Patients]
    A Repiso Ortega et al. Gastroenterol Hepatol 26 (6), 341-6. PMID 12809570. - Review
    Infection with Anisakis simplex should be investigated in patients with abdominal pain after intake of raw fish, ileitis of unclear origin, or eosinophilic gastroenteriti …
  • [Anisakiasis: A Borderline Disorder]
    F Gani et al. Recenti Prog Med 92 (4), 302-6. PMID 11388051. - Review
    Anisakis simplex is a nematode which can parasitize many different kinds of fish or cephalopods (codfish, salmon, tuna, mackerel, hake, etc). Anisakis simplex can cause d …
See all similar articles

Cited by 11 PubMed Central articles

See all "Cited by" articles

Publication types