Expert clinical decision support systems to enhance antimicrobial stewardship programs: insights from the society of infectious diseases pharmacists

Pharmacotherapy. 2005 Aug;25(8):1116-25. doi: 10.1592/phco.2005.25.8.1116.


Health care-associated infections (HAIs) are a leading cause of in-hospital mortality and adverse events such as antimicrobial resistance. These infections place tremendous burdens on the health care system and create situations for misuse of antimicrobial drugs. Recognition of these factors has led professional societies, clinicians, and hospitals to develop programs to improve the management of HAIs and the use of antimicrobial drugs. The clinical literature is replete with examples of these programs, often referred to as antimicrobial stewardship. Traditionally, antimicrobial stewardship programs have relied on manual methods combined with clinical oversight and intervention. The advent of modern health care information technology offers the opportunity to expand the breadth and depth of these programs. Expert clinical decision support systems are the most promising of these information technology advances.

Publication types

  • Review

MeSH terms

  • Anti-Infective Agents / administration & dosage*
  • Anti-Infective Agents / therapeutic use*
  • Cross Infection / epidemiology
  • Decision Support Systems, Clinical*
  • Humans
  • Medical Informatics
  • Terminology as Topic


  • Anti-Infective Agents