Addisonian pigmentation of the oral mucosa

Cutis. 2005 Aug;76(2):97-9.


Cutaneous pigmentation is a hallmark of Addison disease. When present, the hyperpigmentation generally localizes to sun-exposed surfaces. This case highlights a less well-recognized cutaneous feature that is pathognomonic for the disease: oral mucous membrane hyperpigmentation. We describe this unique type of discoloration in detail and contrast it with other forms of oral pigmentation.

Publication types

  • Case Reports

MeSH terms

  • Addison Disease / complications
  • Addison Disease / diagnosis*
  • Child
  • Diagnosis, Differential
  • Female
  • Humans
  • Hyperpigmentation / complications*
  • Mouth Diseases / complications*
  • Mouth Mucosa
  • Tongue Diseases / complications