[A Paradox of a Parasite Prolonging the Life of Its Host. Pearl Mussel Can Cancel the Accelerated Aging Program in Salmon]

Izv Akad Nauk Ser Biol. Jul-Aug 2005;(4):435-41.
[Article in Russian]


A unique case is analyzed when the accelerated aging program (progeria) in salmons (Salmonidae) can be canceled by larval parasite of the gills--freshwater pearl mussel Margaritifera margaritifera. As a result, the maximum age of Salmo fishes hosting the mussel can be as high as 13 years. The mollusk-fish system made it possible to demonstrate that the parasite can inhibit aging of the host and stimulate nonspecific resistance to stress, i.e., can control longevity. The mussel proved to increase the resistance to epitheliomata and cutaneous mycoses. The parasite is perceived to neutralize the senile changes in the regulatory system hypothalamus-pituitary-peripheral endocrine glands-hypothalamus of salmon.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Bivalvia / physiology*
  • Fish Diseases / metabolism
  • Fish Diseases / parasitology*
  • Host-Parasite Interactions / physiology
  • Hypothalamo-Hypophyseal System / metabolism
  • Hypothalamo-Hypophyseal System / parasitology*
  • Longevity* / physiology
  • Salmo salar / metabolism
  • Salmo salar / parasitology*