Tuberculosis: an under-diagnosed aetiological agent in uveitis with an effective treatment

Eye (Lond). 2006 Sep;20(9):1068-73. doi: 10.1038/sj.eye.6702093. Epub 2005 Oct 7.


Purpose: To highlight the diversity of clinical presentations with tubercular uveitis in a nonendemic setting, and discuss the diagnostic approach and an effective treatment.

Method: Descriptive case series.

Results: A total of 12 cases of varied presentations of tubercular uveitis diagnosed over a period of 1 year of which six cases are described in detail. Presentations included choroidal tuberculomas, multifocal choroiditis, recurrent granulomatous uveitis, panuveitis with cystoid macular oedema, and serpiginous choroiditis. All cases had a chronic or recurrent course and responded very well to antitubercular treatment. Diagnosis was mainly assisted by positive tuberculin testing.

Conclusion: A high index of suspicion helps diagnose ocular tuberculosis in areas of low prevalence of the disease. It forms part of the differential diagnosis of any chronic or recurrent uveitis, especially in an at-risk patient. Antitubercular treatment seems highly effective.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Antitubercular Agents / therapeutic use
  • Choroiditis / drug therapy
  • Choroiditis / microbiology
  • Chronic Disease
  • Female
  • Humans
  • Male
  • Middle Aged
  • Panuveitis / drug therapy
  • Panuveitis / microbiology
  • Recurrence
  • Retrospective Studies
  • Tuberculosis, Ocular / diagnosis*
  • Tuberculosis, Ocular / drug therapy
  • Uveitis / drug therapy
  • Uveitis / microbiology*


  • Antitubercular Agents