Antiangiogenic therapy for a large splenic hemangioma

Pediatr Surg Int. 2005 Dec;21(12):1007-10. doi: 10.1007/s00383-005-1533-3. Epub 2005 Oct 8.


Hemangiomas involving the spleen are rare and seldom symptomatic. Treatment options for large lesions usually consist of splenectomy, embolization, or both. Antiangiogenic treatment has not been reported previously as an effective alternative for this type of lesion. We report our experience of successfully using glucocorticoids in an infant with a large hemangioma of the spleen.

Publication types

  • Case Reports

MeSH terms

  • Angiogenesis Inhibitors / therapeutic use*
  • Glucocorticoids / therapeutic use*
  • Hemangioma / diagnostic imaging
  • Hemangioma / drug therapy*
  • Humans
  • Infant
  • Male
  • Prednisone / therapeutic use*
  • Splenic Neoplasms / diagnostic imaging
  • Splenic Neoplasms / drug therapy*
  • Ultrasonography


  • Angiogenesis Inhibitors
  • Glucocorticoids
  • Prednisone