Central neurogenic hyperventilation: a case report and discussion of pathophysiology

Arch Neurol. 2005 Oct;62(10):1632-4. doi: 10.1001/archneur.62.10.1632.


Background: Central neurogenic hyperventilation is a rare condition with poorly understood pathophysiology.

Objective: To describe a patient with central neurogenic hyperventilation caused by an infiltrative brainstem lymphoma.

Conclusion: Based on analysis of this patient and other case reports, we propose that central neurogenic hyperventilation is uniquely the result of infiltrative tumors that stimulate pontine respiratory centers and central chemoreceptors.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / pathology
  • Aged
  • Brain Neoplasms / complications*
  • Brain Neoplasms / pathology*
  • Colorectal Neoplasms / pathology
  • Humans
  • Hyperventilation / etiology*
  • Hyperventilation / physiopathology
  • Lymphoma, B-Cell / complications*
  • Lymphoma, B-Cell / pathology*
  • Male
  • Neoplasms, Multiple Primary / pathology