Nasal and paranasal sinus manifestation of Rosai-Dorfman disease

Rhinology. 2005 Sep;43(3):229-32.


Rosai-Dorfman disease is a rare, idiopathic, benign, histiocytic proliferation usually seen in younger patients. Most commonly neck lymph nodes are involved with a predominant infiltration of sinusoidal histiocytes. Nearly half of the patients have extranodal manifestation. Two cases of Rosai-Dorfman disease involving the nose and the paranasal sinuses are presented. The clinical presentation, radiographic findings, treatment and histological characteristics of the disease are discussed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Histiocytosis, Sinus / diagnostic imaging*
  • Histiocytosis, Sinus / pathology*
  • Histiocytosis, Sinus / therapy
  • Humans
  • Male
  • Middle Aged
  • Nasal Cavity / diagnostic imaging*
  • Nasal Cavity / pathology*
  • Paranasal Sinuses / diagnostic imaging*
  • Paranasal Sinuses / pathology*
  • Radiography