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Case Reports
, 9 (4), 338-40

Effect of Mineralocorticoids on Interdialytic Weight Gain in Hemodialysis Patients With Perdialytic Hypotension

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Case Reports

Effect of Mineralocorticoids on Interdialytic Weight Gain in Hemodialysis Patients With Perdialytic Hypotension

Lucile Mercadal et al. Hemodial Int.

Abstract

Fludrocortisone is recommended in patients with orthostatic hypotension and a benefit has been suggested in hemodialysis patients with severe hypokaliemia. We report 2 patients who suffered from chronic severe perdialytic hypotension resistant to midodrine and who were treated in a long-term period with fludrocortisone. A rise of post-dialytic BP was observed with a decrease of the interdialytic weight gain (IWG). We suggest that the IWG decrease is induced by a lessening of the renin angiotensin aldosterone system that could be less stimulated at the end of the dialysis session because of a better-preserved arterial pressure. The decrease of angiotensin could lessen the feeling of thirst.

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Cited by 1 PubMed Central articles

  • Use of Fludrocortisone for Intradialytic Hypotension
    Y Seo et al. Kidney Res Clin Pract 37 (1), 85-88. PMID 29629281.
    Intradialytic hypotension during dialysis adversely affects a patient's prognosis and increases mortality. We report a case in which intradialytic hypotension that persis …

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