Immunogenicity and safety of inactivated influenza virus vaccine in young children in 2003-2004

Pediatr Infect Dis J. 2005 Oct;24(10):925-7. doi: 10.1097/01.inf.0000180978.66362.d9.

Abstract

This study assessed the safety and immunogenicity of a pediatric formulation of the 2003-2004 inactivated, trivalent, split virion influenza vaccine, administered in a 2-dose schedule in healthy children ages 6-36 months, of whom 94% had protective titers (> or =1/40) to at least 1 antigen. The 2003-2004 split virion influenza vaccine was safe and immunogenic in young children.

Publication types

  • Clinical Trial
  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibodies, Viral / blood*
  • Child, Preschool
  • Humans
  • Immunization Schedule
  • Infant
  • Influenza A virus / immunology*
  • Influenza B virus / immunology*
  • Influenza Vaccines / administration & dosage
  • Influenza Vaccines / adverse effects*
  • Influenza Vaccines / immunology
  • Influenza, Human / prevention & control*
  • Treatment Outcome
  • Vaccination
  • Vaccines, Inactivated / administration & dosage
  • Vaccines, Inactivated / adverse effects*
  • Vaccines, Inactivated / immunology
  • Virion / immunology

Substances

  • Antibodies, Viral
  • Influenza Vaccines
  • Vaccines, Inactivated