An efficient and practical synthesis of bis(indolyl)methanes catalyzed by aminosulfonic acid under ultrasound

Ji-Tai Li; Hong-Guang Dai; Wen-Zhi Xu; Tong-Shuang Li

doi:10.1016/j.ultsonch.2004.12.004

An efficient and practical synthesis of bis(indolyl)methanes catalyzed by aminosulfonic acid under ultrasound

Ultrason Sonochem. 2006 Jan;13(1):24-7. doi: 10.1016/j.ultsonch.2004.12.004.

Authors

Ji-Tai Li¹, Hong-Guang Dai, Wen-Zhi Xu, Tong-Shuang Li

Affiliation

¹ College of Chemistry and Environmental Science, Hebei University, Key Laboratory of Analytical Science and Technology of Hebei Province, Baoding 071002, PR China. orgsyn@mail.hbu.edu.cn

PMID: 16223682
DOI: 10.1016/j.ultsonch.2004.12.004

Abstract

Synthesis of bis(indolyl)methanes via electrophilic substitution reactions of indoles with aromatic aldehydes and ketones catalyzed by aminosulfonic acid was carried out in 23-96% yield at 30-38 degrees C in EtOH aqueous solution under ultrasound irradiation.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Catalysis
Indoles / chemistry*
Indoles / radiation effects
Methane / chemistry*
Methane / radiation effects
Sonication*
Sulfonic Acids / chemistry*
Sulfonic Acids / radiation effects

Substances

Indoles
Sulfonic Acids
sulfamic acid
Methane