A case of primary syphilis in the rectum

J Korean Med Sci. 2005 Oct;20(5):886-7. doi: 10.3346/jkms.2005.20.5.886.


A 30-yr-old man was referred for suspicious rectal cancer because of ulcerated lesions in the rectum and a palpable mass in left inguinal area. Sigmoidoscopy showed two indurated masses and histologic evaluation of biopsy revealed obliterative endarteritis with heavy plasma cell infiltration. Both venereal disease research laboratories (VDRL) and fluorescent treponemal antibody absorption (FTA-ABS) tests were positive. After injection of penicillin G benzathine for 3 weeks, the rectal chancre and the palpable mass disappeared.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Diagnosis, Differential
  • Humans
  • Male
  • Rectal Diseases / complications*
  • Rectal Diseases / drug therapy
  • Rectal Diseases / pathology*
  • Rectal Neoplasms / pathology
  • Syphilis / complications*
  • Syphilis / drug therapy
  • Syphilis / pathology*