Heparin-induced thrombocytopenia: clinical presentations and therapeutic management

Clin Adv Hematol Oncol. 2003 Jun;1(6):356-64.

Abstract

With increasing indications for heparin usage, an understanding of heparin-induced thrombocytopenia (HIT) as a complication of heparin therapy is more essential than ever. Complications of HIT can result in significant morbidity and mortality. We review the clinical presentations of HIT, laboratory and diagnostic workup, and treatment agents available or being evaluated.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Anticoagulants / therapeutic use
  • Comorbidity
  • Disease Management
  • Heparin / adverse effects*
  • Humans
  • Thrombocytopenia / chemically induced*
  • Thrombocytopenia / diagnosis
  • Thrombocytopenia / drug therapy
  • Treatment Outcome

Substances

  • Anticoagulants
  • Heparin